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Sealant showdown: healthy vs. Early-Cavity teeth – which holds up better?

NCT ID NCT07330089

Prevention Sponsor: Foundation University Islamabad Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study will place dental sealants on 420 back teeth in children and teens aged 7 to 18. Half of the teeth are healthy, and half have very early cavities. Researchers will check how well the sealants stay on over 12 months to see if early decay affects retention. The goal is to improve cavity prevention by tailoring follow-up care.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
dental sealant
What this could lead to
If successful, this could help dentists know which teeth need closer follow-up after sealant placement, leading to better cavity prevention.
What could go wrong
This is an observational comparison, not a test of a new treatment. Results may not apply to all patients or settings.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 420 people

The number the study aims to enrol. It can still change while the study runs.

Started

Dec 2025

Expected to finish

Jun 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients reporting to Paedodontics and Operative dentistry department of FUCD\&H will be selected according to inclusion criteria after history, clinical examination.

Ages

7 to 18 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Fully erupted maxillary and mandibular 1st and 2nd molars with antagonist teeth present. * ICDAS score 0,I,II * Age 7 to 18 years * Both genders included Exclusion Criteria: * permanent teeth requiring restorations, * uncooperative patients * patients unwilling for follow-ups * molars withy antagonist teeth not present * mentally and physically handicapped patients * patients with parafunctional habits * patients undergoing orthodontic treatments

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Conditions

The condition(s) this trial relates to.

Dental Enamel Hypomineralization dental enamel hypoplasia van der Woude syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Dental enamel Dental enamel hypomineralization Dental enamel hypoplasia

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Foundation University Islamabad

    RECRUITING

    Islamabad, Federal, 44000, Pakistan