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Gum graft showdown: collagen vs. palate tissue for better implants

NCT ID NCT07080177

Disease control Sponsor: Cairo University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study tests two ways to improve gum tissue around dental implants in adults with missing teeth. One method uses a collagen membrane from cows, the other uses a small piece of tissue from the roof of the mouth. The goal is to see which approach leads to healthier gums and better implant success. Twenty-four participants will be randomly assigned to one of the two procedures.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
xenogeneic collagen membrane (bovine origin) and free gingival graft (from the palate)
What this could lead to
If successful, this could show that a collagen membrane works as well as a traditional gum graft, offering a less invasive option for dental implant patients.
What could go wrong
This is a small, early-stage trial with only 24 participants, so results may not apply to everyone. Graft procedures carry risks like infection or shrinkage.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 24 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Sep 2025

An estimate. Start dates often move.

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 55 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Adults above the age of 18 years. 2. Presence of 2mm or less of keratinized tissue width 3. Sufficient alveolar ridge width minimum of 6 mm 4. Patients with good oral hygiene as evidenced by plaque index (PI)\<1 and showing cooperation or compliance with treatment. Exclusion Criteria: 1. Patients diagnosed with periodontal diseases (Caton et al., 2018). 2. Acute active infection at implant sites 3. Patients with medical conditions that would compromise the surgical procedures; uncontrolled diabetes mellitus, taking intravenous bisphosphonates for treatment of osteoporosis and radiotherapy 4. Patients with parafunctional habits. 5. Smokers (≥10 cigarettes per day),

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Conditions

The condition(s) this trial relates to.

anodontia tooth agenesis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Missing teeth

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • MTI University

    Cairo, Egypt

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Other studies related to the condition(s) this trial covers.