3D-Printed trays promise brighter smiles with less sensitivity
NCT ID NCT07464197
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether 3D-printed custom nightguards whiten teeth better and more comfortably than traditional ones. Forty adults with stained teeth will use a standard whitening gel at home. Researchers will measure color change, tooth sensitivity, and gum irritation to find the best tray design.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
About 40 people
The number the study aims to enrol. It can still change while the study runs.
- Started
-
May 2022
- Expected to finish
-
Jul 2026
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 years and older
- Sex
-
Anyone
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults aged 18 years or older * Good general and oral health * No current medical treatment (self-reported) * No need for surgical, endodontic, periodontal, or restorative dental treatment * At least six upper and six lower anterior teeth free of caries and restorations * Maxillary central incisors with baseline shade A2 or darker * Willingness to follow the study protocol and use the study-provided oral hygiene products/instructions Exclusion Criteria: * Previous tooth bleaching treatment * Orthodontic appliances or prostheses that interfere with treatment * Severe intrinsic discoloration (e.g., tetracycline staining, fluorosis, or endodontically treated teeth with discoloration) * Pregnancy or lactation * Bruxism * Gingival recession, dentin exposure, visible enamel cracks, or other conditions associated with increased sensitivity * Use of anti-inflammatory or analgesic medication during the study period (according to protocol)
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Tooth discoloration are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
-
The places running it
1 site. The list below names each one and where it is.
-
The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
-
A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
-
Clínica Universitària d'Odontologia UIC Barcelona
RECRUITINGSant Cugat del Vallès, BARCELONA, 08195, Spain
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- The whitening wars: peroxide vs Peroxide-Free bleaching put to the test
- Tiny particles in bleaching gel could mean whiter teeth and fewer zings
- Can root canals leave teeth discolored? study measures the change
- Could a gentler solution replace acid for brighter teeth?
- New study reveals best way to erase ugly tooth spots in kids
- New foam toothpaste promises whiter teeth and less pain