Dental adhesive showdown: which bond lasts longer?
NCT ID NCT05497583
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This completed trial tested two types of dental adhesives (acetone-based vs. isopropanol-based) for filling non-carious cervical lesions—tooth wear not caused by decay. Twenty-eight adults received fillings and were followed for 18 months to see which adhesive held up better. The goal was to find a more durable bond to improve long-term dental restoration success.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Acetone-based HEMA-free universal adhesive and isopropanol-based HEMA-free universal adhesive
- What this could lead to
- If one adhesive performs better, it could lead to more durable dental fillings for non-carious lesions, reducing the need for replacements.
- What could go wrong
- This is a small, early-stage study with only 28 participants, so results may not apply to everyone. The outcome focuses on short-term durability, not long-term success.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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28 people
The number who actually took part.
- Started
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Jan 2023
- Finished
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Nov 2024
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 60 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Participants had to be in good general health, be at least 18 years old * have an acceptable oral hygiene level * Participants were required to have NCCLs in different teeth preferably anterior or posterior that needed to be restored. * These lesions had to be noncarious * deeper than 1 mm * involve both the enamel and dentin of vital teeth without mobility. Exclusion Criteria: * Uncooperative behavior, limits the use of adhesive due to hampering of adequate field or isolation techniques throughout the procedure. * Patients allergic to the adhesive material. Patients with extremely poor oral hygiene * severe or chronic periodontitis * heavy bruxism habits * Pulp involvement
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Faculty of Dentistry, Cairo University
Cairo, Egypt