Dental adhesive showdown: which bond lasts longer?

NCT ID NCT05497583

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed trial tested two types of dental adhesives (acetone-based vs. isopropanol-based) for filling non-carious cervical lesions—tooth wear not caused by decay. Twenty-eight adults received fillings and were followed for 18 months to see which adhesive held up better. The goal was to find a more durable bond to improve long-term dental restoration success.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Acetone-based HEMA-free universal adhesive and isopropanol-based HEMA-free universal adhesive

What this could lead to

If one adhesive performs better, it could lead to more durable dental fillings for non-carious lesions, reducing the need for replacements.

What could go wrong

This is a small, early-stage study with only 28 participants, so results may not apply to everyone. The outcome focuses on short-term durability, not long-term success.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

alopecia universalis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Faculty of Dentistry, Cairo University

    Cairo, Egypt