Bone drug boosts immunotherapy in advanced melanoma trial
NCT ID NCT03620019
First seen Mar 29, 2026 · Last updated May 20, 2026 · Updated 8 times
Summary
This study tested whether adding denosumab (a bone-strengthening drug) to standard immunotherapy (pembrolizumab or nivolumab) could help control advanced melanoma. 25 adults with stage III or IV melanoma that could not be removed by surgery took part. The goal was to see if denosumab could increase immune cells that attack the tumor, potentially making the immunotherapy work better.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Dartmouth-Hitchcock Medical Center
Manchester, New Hampshire, 03104, United States
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UNC Lineberger Comprehensive Cancer Center
Chapel Hill, North Carolina, 27599, United States
Conditions
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