Could a bone drug boost sperm? new trial shows promise
NCT ID NCT06300229
First seen Jan 06, 2026 · Last updated May 24, 2026 · Updated 19 times
Summary
This study tested whether denosumab, a drug usually used for bone health, can improve semen quality in men with very low sperm counts. 42 infertile men with severe oligospermia (sperm concentration between 0.01 and 2 million per mL) and a specific blood marker (AMH) were enrolled. The main goal was to see if sperm concentration increased after 80 days of treatment.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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Division of Translational Endocrinology, Department of Endocrinology and Internal Medicine
Copenhagen, Denmark
Conditions
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