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New hope to halt childhood bone disease progression

NCT ID NCT05419050

Summary

This study tested whether a medication called denosumab could slow or stop the progression of fibrous dysplasia, a rare bone disease, in children. Fifteen children aged 4 to 14 received denosumab injections every four weeks for nearly a year. Researchers measured changes in bone lesions, strength, mobility, pain, and quality of life to see if the treatment was effective and safe.

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Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States

Conditions

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