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Scientists track dengue in kids to stop Mosquito-Borne illness

NCT ID NCT03534245

Knowledge-focused Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Sep 17, 2026 · Updated 21 times

Summary

This study followed 775 healthy children aged 2-9 in Cambodia over three years to learn how mosquitoes spread dengue and other viruses. Researchers took blood samples every wet and dry season to check for past or current infections. The goal was to understand why young children get sick more often and to lay the groundwork for future prevention efforts.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this research could help design better ways to prevent dengue in children, like vaccines or mosquito control programs.
What could go wrong
This is an observational study, not a treatment trial. It only measures infections and immune responses, so it won't directly lead to a cure or new drug.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

775 people

The number who actually took part.

Started

Jul 2018

Finished

Jan 2022

Lead sponsor

A government research agency

The lead sponsor is the US National Institutes of Health.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Community-based cohort of children from the town of Chbar Mon in Kampong Speu, Cambodia, who live within 5.5 km to the Kampong Speu District Referral Hospital.@@@

Ages

2 to 9 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

* INCLUSION CRITERIA: In order to be eligible to participate in this study, an individual must meet all of the following criteria: 1. Provision of signed and dated informed consent form 2. Stated willingness to comply with all study procedures and availability for the duration of the study 3. Male or female, aged 2-9 years 4. Live within approximately 5.5 km of study site 5. In good general health as evidenced by medical history 6. Willing to allow biological samples to be stored for future research. EXCLUSION CRITERIA: 1. Current or prior use within last 6 months of any immunosuppression (e.g. intravenous immunoglobulin, steroids, interferon therapy) 2. Treatment with another investigational drug, vaccine, or other intervention within six months of screening

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Conditions

The condition(s) this trial relates to.

chikungunya dengue disease Zika virus infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Dengue fever

Contacts and locations

Locations

  • Kampong Speu Referral Hospital

    Chbar Mon, Kampong Speu, Cambodia

More trials for these conditions

Other studies related to the condition(s) this trial covers.