Herbal granules take on a stomach condition that raises cancer risk
NCT ID NCT05209633
First seen Jul 27, 2026 · Last updated Jul 28, 2026 · Updated 1 time
Summary
This trial tests whether Dendrobii granules, a traditional Chinese herbal remedy, can improve chronic atrophic gastritis — a condition where the stomach lining thins and raises the risk of stomach cancer. Twenty adults with the condition will receive either the granules or a placebo for 18 weeks. The goal is to see if the treatment can reverse precancerous changes in the stomach lining.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Dendrobii granules (a traditional Chinese medicine preparation)
- What this could lead to
- If effective, Dendrobii granules could offer a new treatment option for chronic atrophic gastritis and potentially reduce the risk of progression to gastric cancer.
- What could go wrong
- This is a small, early-phase trial with only 20 participants, so results may not apply broadly. The treatment is based on traditional Chinese medicine and lacks large-scale evidence.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Phase 2
Tests whether the treatment actually works, and watches for side effects, in a larger group.
- Participants
-
20 people
The number who actually took part.
- Started
-
Nov 2022
- Finished
-
Nov 2024
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 65 years
- Sex
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Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Fulfill the diagnosis of chronic atrophic gastritis; * TCM syndrome differentiation is deficiency of both qi and yin; * Aged between 18 and 65 years old, regardless of gender; * Volunteer to participate in this clinical trial and sign an informed consent form. Exclusion Criteria: * Patients with peptic ulcer, acid reflux, etc. who need PPI treatment; * Patients with high-grade intraepithelial neoplasia of gastric mucosa or suspected malignant transformation in pathological diagnosis; * Those who have received anti-HP treatment and related treatments in the past two weeks; * Diabetic patients; * Patients with severe heart, liver, kidney, lung, blood system diseases, abnormal renal function Cr test with clinical significance, and liver function ALT ≥ 1.5 times the upper limit of the normal reference value; * People with allergies or a history of allergies to multiple drugs (two or more or the known ingredients in the drug); * Those planning to become pregnant, pregnant or breast-feeding; * Patients with mental illness; * Those who have participated in other drug clinical trials within the past 3 months; * The investigator believes that it is not suitable to participate in this clinical trial.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
The Chinese University of Hong Kong
Hong Kong, Hong Kong
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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