New brain surgery technique could make Parkinson's treatment safer and more comfortable
NCT ID NCT04884412
First seen Jan 02, 2026 · Last updated Jun 19, 2026 · Updated 23 times
Summary
This study tested a new way to place electrodes in the brain for deep brain stimulation (DBS) in people with Parkinson's disease. Instead of using awake brain recordings to guide placement, the new method uses a special MRI-based target calculated by a computer model. The trial involved 128 patients and compared the new method to the standard procedure. The goal was to see if the new approach could improve motor symptoms just as well, while being safer and more comfortable for patients.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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CHU Amiens
Amiens, France
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CHU Marseille
Marseille, 13005, France
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CHU de Bordeaux
Bordeaux, France
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CHU de Nice
Nice, France
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CHU de Rouen
Rouen, France
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CHU de Strasbourg
Strasbourg, France
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CHU de Toulouse
Toulouse, France
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Hospices Civils de Lyon
Lyon, France
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Deep brain stimulation surgery with a new MRI-based targeting method
What this could lead to
If successful, this could make deep brain stimulation surgery safer and more comfortable for Parkinson's patients by avoiding the need for awake brain recordings.
What could go wrong
This is a completed trial with 128 participants, but the new method may not be as effective as the standard approach, and results may vary across different medical centers.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.