Brain wave study aims to decode imagined movements for stroke recovery
NCT ID NCT06469463
First seen Jun 26, 2026 · Last updated Jul 29, 2026 · Updated 3 times
Summary
This study investigates how brain activity changes when people imagine moving their wrist. Researchers will use advanced brain scans (MRI and MEG) to create personalized models of these signals, then test if they can decode imagined movements using simpler EEG recordings. The goal is to improve brain-computer interfaces that could help stroke patients with arm weakness. The study includes healthy adults and a small group of stroke patients.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this research could lead to better brain-computer interfaces that help stroke patients regain arm movement through mental practice.
- What could go wrong
- This is an early-stage study with only 35 participants, focused on understanding brain signals rather than testing a treatment. The results may not directly translate into a therapy.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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30 people
The number who actually took part.
- Started
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Mar 2026
- Finished
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Jul 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Control group: * Healthy subjects with age\> 18, male or female. * Right handed (Due to the fact that unlike right-handed people, left-handed people tend to have more complicated somatotopic organization of the motor cortex, we will avoid confounding observed differences to differences attributable to anatomic factors). * Registered with the French healthcare system. * Motivated to participate in the study. * Normal or corrected vision. * Adequate knowledge of French language to be able to follow directions. * Subjects must be able to listen and understand the study instructions. * Subjects must be able to give written informed consent before participation. * No history of neurological or psychiatric disease. * No physical disability of the arms or wrists. * No use of drugs affecting the central nervous system or self-reported abuse of any drugs. Patient group : * Male or female stroke patients over 18 years old. * Stroke patients must be not be in the acute phase of stroke. * Right-handed. * Having motor disorders in at least one of the upper limbs following the stroke, possibly with moderate accompanying deficits but no cognitive deficits. * Entitled to a social security scheme. * Motivated to participate in the study. * Having normal or corrected vision. * Having a sufficient understanding of the French language to be able to follow directions. * Able to listen and understand study instructions. * Able to give their written informed consent before participating. Exclusion Criteria: * Subjects with characteristics incompatible with MEG and MRI : 1\. Claustrophobia. * Subjects with motor impairment (only applies to control group), severe traumatic brain injury. * Subjects with chronic stroke (applies to both groups). * Subjects history of skin disease or skin allergies (multiple or severe). * Subjects who: 1. have had an MRI within 2 weeks prior to the experiment. 2. have implanted materials (any dental apparatus containing metal including or root canals or any metallic object, pacemaker, cochlear implanted in the body). * Subjects working with metals in their professional lives. * Pregnant or lactating women Pregnant or lactating women (check with a urinary test). * Subjects who are not able to tolerate sitting for longer than 2 hours (the estimated length of an experimental session is about 2h30mins). * Subjects with alcohol dependence (no consumption of alcohol or drugs at least 24 hours prior to the day of experiments). * Subjects currently taking a medication that may have a strong effect on MEG or EEG recordings (e.g., antidepressants, stimulant medication, etc). * Subjects who, in the opinion of the investigator, are not able or willing to comply with the protocol. * Persons under guardianship or curatorship. * Persons in emergency situations who cannot give their consent. * Subjects under 18 years of age. * Subjects under legal protection measures. * Volunteers with contraindications to MEG examination * Pacemaker. * Implanted pump including insulin pump. * Neurostimulator. * Cochlear implants or other hearing aids. * Metal prosthesis. * Intracerebral / surgical aneurysm clips. * Ocular or cerebral ferromagnetic foreign bodies in the upper body. * Neurosurgical ventriculoperitoneal shunt valves.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Centre de Recherche en Neurosciences de Lyon - INSERM U1028
Bron, 69675, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Moving patterns may help stroke survivors read faster
- Vibrating wearables put stroke walking to the test
- Robot plus electrical stimulation aims to rebuild arm movement after stroke
- Can a checklist and heart monitor stop repeat strokes?
- Heart hole or stroke trigger? global registry tracks who gets closure and what happens next