New tool aims to help blood clot patients choose wisely on blood thinners
NCT ID NCT07659106
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a decision aid for people who have had a first blood clot and must decide whether to stop or continue blood thinners after at least 3 months of treatment. The aid provides balanced information on risks and benefits and helps clarify personal values. Researchers will measure whether it reduces confusion and improves knowledge in 850 participants across 12 Canadian clinics.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Patient decision aid (behavioural intervention)
- What this could lead to
- If successful, this decision aid could help patients and doctors make more informed, values-based choices about blood thinner use after a first blood clot.
- What could go wrong
- This is a behavioural study, not a drug trial, so it won't directly treat or cure the condition. The aid may not change outcomes like clot recurrence or bleeding.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 850 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Sep 2026
An estimate. Start dates often move.
- Expected to finish
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Mar 2029
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age 18 years or older * First episode of objectively confirmed unprovoked or weakly provoked venous thromboembolism (VTE) * Objectively confirmed proximal deep vein thrombosis and/or segmental or greater pulmonary embolism * Completed at least 3 months of therapeutic anticoagulation and currently receiving anticoagulation * Enrollment within 12 months of diagnosis of the index/qualifying VTE event * Able to provide written informed consent * Able to participate in shared decision-making in English or French Exclusion Criteria: * Recurrent unprovoked or weakly provoked VTE I(i.e. multiple unprovoked/weakly provoked VTE) * Index/qualifying VTE is a strongly provoked VTE (e.g., associated with major surgery, major trauma, plaster cast immobilization, or prolonged bed rest) * Index/qualifying VTE associated with a persistent strong provoking risk factor (e.g., active cancer or ongoing immobility) * Women at very low recurrence risk (HERDOO2 score 0-1) * High bleeding risk such that anticoagulation should be discontinued * Requirement for long-term anticoagulation for another indication (e.g., atrial fibrillation) * Prior dedicated long-term anticoagulation Decision Visit regarding anticoagulation duration
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
5 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Ottawa Hospital - General Campus
Ottawa, Ontario, K1H 8L6, Canada
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Research Institute of McGill University Health Centre
Montreal, Quebec, H4A 3J1, Canada
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Sir Mortimer B. Davis Jewish General Hospital
Montreal, Quebec, H3T 1E2, Canada
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University of Calgary
Calgary, Alberta, T2N 1N4, Canada
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Vancouver General Hospital
Vancouver, British Columbia, V5Z 1N1, Canada
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can a new Five-Category system predict which pulmonary embolism patients will crash?
- One shot to stop blood clots? new injection put to the test
- Which blood thinner is safer for lung clots? a Head-to-Head test
- A new exercise plan aims to get pulmonary embolism survivors back on their feet
- Can a tiny device suction out dangerous blood clots?