New drug shows promise for Hard-to-Treat cancers in early trial
NCT ID NCT05109975
First seen Nov 01, 2025 · Last updated May 24, 2026 · Updated 32 times
Summary
This study is testing an experimental drug called Debio 0123 in 66 adults with advanced solid tumors that have grown after standard treatments or have no standard options. The first part finds the safest dose, and the second part checks safety and whether the drug can shrink tumors. It is an early-phase trial, so the main goals are safety and dosing, not a cure.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Clinica Universidad de Navarra
Madrid, 28027, Spain
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Clinica Universidad de Navarra
Pamplona, 31008, Spain
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David H. Koch Center for Cancer Care at Memorial Sloan Kettering Cancer Center
New York, New York, 10021, United States
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Froedtert Hospital and the Medical College of Wisconsin
Milwaukee, Wisconsin, 53226, United States
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Hospital Clinico Universitario de Valencia
Valencia, 46010, Spain
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Hospital Universitari Vall d'Hebron
Barcelona, 08035, Spain
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Hospital Universitario 12 de Octubre
Madrid, 28041, Spain
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Hospital Universitario La Paz
Madrid, 28046, Spain
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Institut Catala de Oncologia
Girona, 17007, Spain
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Istituto Oncologico della Svizzera italiana - Ente Ospedaliero Cantonale
Bellinzona, 6500, Switzerland
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Kantonsspital St. Gallen, Rorschacher Strasse 95
Sankt Gallen, 9007, Switzerland
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START Madrid. Hospital Fundación Jimenez Diaz
Madrid, 28040, Spain
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South Texas Accelerated Research Therapeutics (START)
San Antonio, Texas, 78229, United States
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South Texas Accelerated Research Therapeutics (START) Midwest
Grand Rapids, Michigan, 49546, United States
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Universitätsspital Zürich, Dermatologische Klinik
Zurich, 8058, Switzerland
Conditions
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