New cancer drug debio 0123 tested in early trial

NCT ID NCT05109975

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage study tested a new drug called Debio 0123 in 66 adults with advanced solid tumors that had stopped responding to standard treatments. The main goals were to find the safest dose and to check for side effects and any signs that the drug could shrink tumors. The study was terminated early, so results are limited.

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Conditions

The condition(s) this trial relates to.

endometrial serous adenocarcinoma fallopian tube cancer neoplasm ovarian carcinoma primary peritoneal carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Clinica Universidad de Navarra

    Madrid, 28027, Spain

  • Clinica Universidad de Navarra

    Pamplona, 31008, Spain

  • David H. Koch Center for Cancer Care at Memorial Sloan Kettering Cancer Center

    New York, New York, 10021, United States

  • Froedtert Hospital and the Medical College of Wisconsin

    Milwaukee, Wisconsin, 53226, United States

  • Hospital Clinico Universitario de Valencia

    Valencia, 46010, Spain

  • Hospital Universitari Vall d'Hebron

    Barcelona, 08035, Spain

  • Hospital Universitario 12 de Octubre

    Madrid, 28041, Spain

  • Hospital Universitario La Paz

    Madrid, 28046, Spain

  • Institut Catala de Oncologia

    Girona, 17007, Spain

  • Istituto Oncologico della Svizzera italiana - Ente Ospedaliero Cantonale

    Bellinzona, 6500, Switzerland

  • Kantonsspital St. Gallen, Rorschacher Strasse 95

    Sankt Gallen, 9007, Switzerland

  • START Madrid. Hospital Fundación Jimenez Diaz

    Madrid, 28040, Spain

  • South Texas Accelerated Research Therapeutics (START)

    San Antonio, Texas, 78229, United States

  • South Texas Accelerated Research Therapeutics (START) Midwest

    Grand Rapids, Michigan, 49546, United States

  • Universitätsspital Zürich, Dermatologische Klinik

    Zurich, 8058, Switzerland