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New drug combo targets Hard-to-Treat cancers

NCT ID NCT03968653

First seen Nov 01, 2025 · Last updated May 23, 2026 · Updated 37 times

Summary

This study tested an experimental oral drug (Debio 0123) combined with the chemotherapy carboplatin in 76 people with advanced solid tumors that had worsened after prior platinum-based treatment. The goal was to find the safest dose and check for side effects and early signs of tumor shrinkage. The study was terminated early, so results are limited.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Clinica Universidad de Navarra

    Madrid, 28027, Spain

  • Clinica Universidad de Navarra - Pamplona

    Pamplona, 31008, Spain

  • Hospital Universitario Virgen de la Victoria

    Málaga, 29010, Spain

  • Hospital Vall Hebrón, Unidad de Investigación en Terapia Molecular (UITM)

    Barcelona, 08035, Spain

  • Instituto Valenciano de Oncologia

    Valencia, 46009, Spain

  • Leiden University Medical Center, Dept. of Clinical Oncology

    Leiden, 2333, Netherlands

  • Radboud university medical center

    Nijmegen, 6525, Netherlands

  • University Medical Center Groningen

    Groningen, 9713, Netherlands

Conditions

Explore the condition pages connected to this study.