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Could smaller surgery after immunotherapy spare head and neck cancer patients?

NCT ID NCT07369882

First seen Jan 28, 2026 · Last updated May 24, 2026 · Updated 11 times

Summary

This study compares a less extensive surgery (de-escalated) to standard surgery for people with advanced head and neck cancer who have already responded well to immunotherapy and chemotherapy. The goal is to see if the smaller surgery can control the cancer just as well while improving quality of life and preserving important functions like swallowing and speech. About 60 adults will take part, and the study will track cancer return, survival, and daily living outcomes for up to 5 years.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Sun Yat-sen Memorial Hospital, Sun Yat-sen University

    RECRUITING

    Guangzhou, Guangdong, 510120, China

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.