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Timing of surgery could change lives for diverticulitis patients

NCT ID NCT05942833

Disease control Sponsor: Kepler University Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether having surgery soon after a severe diverticulitis attack (within 7-10 days) leads to better quality of life than waiting 6-8 weeks. About 136 patients with complicated or recurrent diverticulitis will be randomly assigned to one of the two timing groups. Researchers will track recovery, complications, and overall well-being using standard questionnaires.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
sigmoid resection (surgery)
What this could lead to
If early surgery proves better, patients with severe diverticulitis could recover faster and have a better quality of life.
What could go wrong
This is a small, early-phase trial with only 136 participants, so results may not apply to everyone. Surgery always carries risks like infection or complications.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 136 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2023

Expected to finish

Jul 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Informed consent to participate in the study * CDD Type 2a, 2b: acute complicated left-sided diverticulitis * CDD Type 3b: relapsing diverticulitis without complications (\>2 episodes within 2 years) * Acute presentation * Inflammation located in the left-sided colon * Inflammation is CT proven or ultrasound confirmed from experienced radiologists Exclusion Criteria: * \< 18 years * Pregnancy * BMI \> 55kg/m2 * Current colorectal carcinoma in the left-sided colon * Oral and/or intravenous corticosteroid * Ongoing chemotherapy * Status post left hemicolectomy * Patients who cannot take care of themselves at home or are unable to follow instructions * Patients who are not fit for surgery (anesthesia, expert knowledge from specialists) and will not benefit from surgery

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Conditions

The condition(s) this trial relates to.

diverticulitis diverticulitis of colon

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Diverticulitis of sigmoid

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    4 sites in 2 countries. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Kepler University Hospital

    RECRUITING

    Linz, Upper Austria, 4020, Austria

  • Krankenhaus Barmherzige Schwestern Linz

    RECRUITING

    Linz, Upper Austria, 4010, Austria

  • Ordensklinikum Elisabethinen Linz

    RECRUITING

    Linz, Austria, 4020, Austria

  • Universitätsklinikum Mannheim

    NOT_YET_RECRUITING

    Mannheim, Mannheim, 68167, Germany

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