Blood markers may guide septic shock treatment in new pilot study

This study looked at 40 adults with septic shock (a severe infection causing very low blood pressure) to see if two blood markers, renin and DPP3, can predict who will respond better to a drug called angiotensin II versus standard blood-pressure-raising medicines. The goal was not to cure sepsis but to learn if these markers can help doctors choose the right treatment faster. Participants were randomly assigned to receive either angiotensin II or usual care, and researchers measured blood pressure response after 3 hours.