New hope for rare kidney disease: daratumumab trial aims to stop protein leak
NCT ID NCT05654506
First seen Nov 01, 2025 · Last updated May 20, 2026 · Updated 25 times
Summary
This study tests if daratumumab can help people with a rare kidney disease called PGNMID, where abnormal proteins damage the kidneys. The goal is to reduce protein in the urine and improve kidney function. About 40 adults with confirmed PGNMID and significant protein in their urine will receive the drug and be monitored for safety and effectiveness over 12 months.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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Mayo Clinic
RECRUITINGJacksonville, Florida, 32224, United States
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Mayo Clinic
RECRUITINGRochester, Minnesota, 55905, United States
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Oregon Health and Science University
NOT_YET_RECRUITINGPortland, Oregon, 97239, United States
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University North Carolina at Chapel Hill
RECRUITINGChapel Hill, North Carolina, 27599, United States
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Conditions
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