New hope for hard-to-treat myeloma patients

NCT ID NCT02626481

Completed Disease control Sponsor: University Hospital, Lille Source: ClinicalTrials.gov ↗

First seen Apr 08, 2026 · Last updated May 26, 2026 · Updated 8 times

Summary

This study tested a combination of daratumumab and dexamethasone in 64 adults with multiple myeloma that had stopped responding to three previous treatments. The goal was to see how many patients achieved a partial response or better. The treatment aims to control the disease, not cure it, and side effects were closely monitored.

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Contacts and locations

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Locations

AZ ST Jan hematology department

Bruges, 8000, Belgium
CHRU , Hôpital Claude Huriez

Lille, France
CHRU - Hôpital du Bocage (Amiens)

Amiens, 49033, France
CHRU Côte de Nacre

Caen, 14033, France
CHRU, Hôpital A.Michallon

Grenoble, 38043, France
CHRU-Hôpital Sud d'Amiens

Amiens, 80054, France
CHU - Hôpital St Antoine

Paris, 75571, France
CHU Dinant Godinne | UCL Namur asbl

Yvoir, 1 - 5530, Belgium
CHU de la milétrie

Poitiers, 86000, France
Centre Hospitalier Général

Dunkirk, 59 385, France
Centre Hospitalier Lyon sud

Pierre-Bénite, 69495, France
Centre Hospitalier William Morey

Chalon-sur-Saône, 71100, France
Clinique - ICH CHU de Brest Hôpital Morvan

Brest, 29609, France
Curie Institut

Paris, 75248, France
Département d'Hématologie et Oncologie Hôpitaux Universitaires de Strasbourg

Strasbourg, 67091, France
Hematologie Laarbeeklaan

Brussels, 101 - 1090, Belgium
Hopital E Muller

Mulhouse, 68100, France
Hopital J Monod Sce Rhumato Nord

Montivilliers, 76290, France
Hématologie CHRU IUCT Oncopole

Toulouse, 31100, France
Hématologie Clinique CHU DIJON

Dijon, 21000, France
Hôpital Avicenne

Bobigny, 93009, France
Hôpital R.Debré

Reims, 51032, France
Hôpital Saint-Louis

Paris, 75475, France
Hôpital d'instruction des armées Percy

Clamart, 92141, France
Hôpital de Pontchaillou

Rennes, 35033, France
Hôpital du Haut Lévêque Centre François Magendie

Bordeaux, 33604, France
Hôpitaux de Brabois

Vandœuvre-lès-Nancy, 54511, France
Institut Paoli Calmette

Marseille, 13273, France
Jules Bordet Institute

Brussels, B - 1000, Belgium
Maladies du sang CHRU Hôtel Dieu

Nantes, 44035, France
Médecine interne Centre hospitalier départemental

La Roche-sur-Yon, 85025, France
Onco-hématologie CHRU Hôpital Bretonneau

Tours, 37044, France
Polyclinique Bordeaux Nord Aquitaine

Bordeaux, 33300, France
Sce Hématologie Thérapie Cellulaire CHU Limoges

Limoges, 87000, France
Service Hématologie CHRU Montpellier

Montpellier, 34090, France
Service Hématologie Centre Hospitalier Yves le Foll

Saint-Brieuc, 22000, France
Service d'Hématologie CHV André Mignot

Le Chesnay, 78157, France
Service d'Hématologie Clinique Institut de Cancérologie Lucien Neuwirth

Saint-Priest-en-Jarez, 42270, France
URC/CIC Paris Descartes Necker-Cochin

Paris, 75015, France
Unité de Recherche Clinique - CH Périgueux

Périgueux, 24019, France
service hématologie CH Bretagne Atlantique

Vannes, 56017, France

Conditions

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MULTIPLE MYELOMA