Experimental heart drug targets inherited heart muscle weakness
NCT ID NCT07210723
Summary
This study is testing whether a new medication called danicamtiv can help people with a genetic form of dilated cardiomyopathy, where the heart muscle becomes weak and enlarged. About 332 participants will take either danicamtiv or a placebo pill daily for six months while researchers measure changes in heart function, exercise capacity, and symptoms. The goal is to see if this drug can improve heart pumping ability and quality of life for people with this inherited condition.
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Contacts and locations
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Study contacts
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Contact
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Locations
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AP-HP Hopital Pitie-Salpetriere
RECRUITINGParis, 75013, France
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Aarhus University Hospital
RECRUITINGAarhus, 8200, Denmark
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Brigham and Women's Hospital
RECRUITINGBoston, Massachusetts, 02115, United States
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Cardiovascular Clinical Research Facility (CCRF)
RECRUITINGOxford, OX3 9DU, United Kingdom
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Cedars Sinai
RECRUITINGLos Angeles, California, 90048, United States
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Hammersmith Hospital, Imperial College of London
RECRUITINGLondon, W12 0HS, United Kingdom
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Henry Ford Health System
RECRUITINGDetroit, Michigan, 48202, United States
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Hospital Clinico Universitario Virgen de la Arrixaca
RECRUITINGMurcia, 30120 El Palmar,, Spain
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Hospital Universitari de Bellvitge
RECRUITINGBarcelona, 08907, Spain
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Hospital Universitario Puerta de Hierro
RECRUITINGMajadahonda, Madrid, 20222, Spain
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Hospital Universitario Son Llatzer
RECRUITINGPalma de Mallorca, 7198, Spain
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Hospital Universitario Vall d'Hebron
RECRUITINGHorta-Guinardó, Barcelona, 08035, Spain
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Hospital Universitario Virgen del Rocio
RECRUITINGSeville, 41013, Spain
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Hospital Universitario de A Coruña
RECRUITINGA Coruña, 15006, Spain
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Louisiana State University (LSU) Health Sciences Center
RECRUITINGNew Orleans, Louisiana, 70112, United States
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Mayo Clinic Rochester
RECRUITINGRochester, Minnesota, 55905, United States
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MedStar Washington Hospital Center
RECRUITINGWashington D.C., District of Columbia, 20010, United States
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NHS Greater Glasgow and Clyde
RECRUITINGGlasgow, G12 0YN, United Kingdom
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Royal Brompton Hospital
RECRUITINGLondon, SW3 6NP, United Kingdom
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Sodersjukhuset AB
RECRUITINGStockholm, 11883, Sweden
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The Ohio State University Wexner Medical Center
RECRUITINGColumbus, Ohio, 43210, United States
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UCSF
RECRUITINGSan Francisco, California, 94158, United States
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University of Alabama Birmingham
RECRUITINGBirmingham, Alabama, 35233, United States
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University of Nebraska Medical Center
RECRUITINGOmaha, Nebraska, 68106, United States
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University of Pennsylvania
RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
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Washington University in St. Louis
RECRUITINGSt Louis, Missouri, 63110, United States
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Conditions
Explore the condition pages connected to this study.