New drug trial targets root cause of inherited heart failure

NCT ID NCT07210723

Recruiting now Disease control Sponsor: Kardigan, Inc. Source: ClinicalTrials.gov ↗

Summary

This study is testing an investigational drug called danicamtiv for people with a genetic form of dilated cardiomyopathy, a condition where the heart muscle is weak and enlarged. About 332 participants will take either danicamtiv or a placebo pill daily for six months to see if the drug improves how well the heart works and helps people exercise better. The goal is to find a new treatment specifically for this inherited heart condition, which currently has no approved targeted therapies.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Brigham and Women's Hospital
RECRUITING

Boston, Massachusetts, 02115, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Cedars Sinai
RECRUITING

Los Angeles, California, 90048, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Hammersmith Hospital, Imperial College of London
RECRUITING

London, W12 0HS, United Kingdom

Contact Phone: •••-•••-•••• Email: •••••@•••••
Henry Ford Health System
RECRUITING

Detroit, Michigan, 48202, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Hospital Clinico Universitario Virgen de la Arrixaca
RECRUITING

Murcia, 30120 El Palmar,, Spain

Contact Phone: •••-•••-•••• Email: •••••@•••••
Hospital Universitario Puerta de Hierro
RECRUITING

Majadahonda, Madrid, 20222, Spain

Contact Phone: •••-•••-•••• Email: •••••@•••••
Hospital Universitario Vall d'Hebron
RECRUITING

Horta-Guinardó, Barcelona, 08035, Spain

Contact Phone: •••-•••-•••• Email: •••••@•••••
Hospital Universitario Virgen del Rocio
RECRUITING

Seville, 41013, Spain

Contact Phone: •••-•••-•••• Email: •••••@•••••
Hospital Universitario de A Coruña
RECRUITING

A Coruña, 15006, Spain

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Mayo Clinic Rochester
RECRUITING

Rochester, Minnesota, 55905, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
MedStar Washington Hospital Center
RECRUITING

Washington D.C., District of Columbia, 20010, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
NHS Greater Glasgow and Clyde
RECRUITING

Glasgow, G12 0YN, United Kingdom

Contact Phone: •••-•••-•••• Email: •••••@•••••
Royal Brompton Hospital
RECRUITING

London, SW3 6NP, United Kingdom

Contact Phone: •••-•••-•••• Email: •••••@•••••
The Ohio State University Wexner Medical Center
RECRUITING

Columbus, Ohio, 43210, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
UCSF
RECRUITING

San Francisco, California, 94158, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
University of Alabama Birmingham
RECRUITING

Birmingham, Alabama, 35233, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
University of Pennsylvania
RECRUITING

Philadelphia, Pennsylvania, 19104, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Washington University in St. Louis
RECRUITING

St Louis, Missouri, 63110, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.

SYMPTOMATIC GENETIC DILATED CARDIOMYOPATHY