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Iron pills every other day? new trial tests a gentler approach for anemia in pregnancy

NCT ID NCT07657455

Disease control Sponsor: Pakistan Air Force (PAF) Hospital Islamabad Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study will test whether taking oral iron supplements every other day works as well as taking them daily for pregnant women with iron deficiency anemia in their second trimester. About 184 women will be randomly assigned to one of two dosing schedules for four weeks. Researchers will measure changes in hemoglobin and ferritin levels, track how well women stick to the regimen, and monitor stomach-related side effects.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Ferrous sulfate (oral iron supplement)
What this could lead to
If it works, this could show that taking iron every other day is just as effective as daily dosing, with fewer side effects and better adherence for pregnant women with anemia.
What could go wrong
This is a small, early-stage trial (184 participants) that hasn't started yet. Results may not apply to all pregnant women, and the four-week duration is too short to assess long-term outcomes or safety.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 184 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Sep 2026

An estimate. Start dates often move.

Expected to finish

Feb 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 40 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Aged 18 to 40 years * Pregnant women in the second trimester (13 to 27 weeks gestation) * Hemoglobin below 11 g/dL with serum ferritin below 30 ng/mL * Singleton pregnancy Exclusion Criteria: * Known congenital or acquired hemoglobin disorders (e.g., thalassemia, hemoglobinopathies) * Chronic diseases affecting hemoglobin levels (e.g., chronic kidney disease, inflammatory disorders) * Bleeding disorders or a history of frequent blood loss * Gastrointestinal conditions impairing nutrient absorption (e.g., celiac disease or other malabsorption syndromes) * Currently receiving parenteral iron * Requiring blood transfusion

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Conditions

The condition(s) this trial relates to.

iron deficiency anemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Anemia in pregnancy Iron deficiency anemia

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Pakistan Air Force (PAF) Hospital Islamabad

    Islamabad, Pakistan

More trials for these conditions

Other studies related to the condition(s) this trial covers.