New drug DA-3501 takes on tough cancers in first human trial
NCT ID NCT07481357
First seen Mar 24, 2026 · Last updated Jun 20, 2026 · Updated 12 times
Summary
This early-phase trial is testing an experimental drug called DA-3501 in people with advanced stomach, gastro-esophageal junction, or pancreatic cancers that have a specific protein (CLDN18.2). The main goals are to find a safe dose and see if the drug can shrink tumors. Participants receive the drug by IV once every three weeks. Because this is a first-in-human study, the focus is on safety and dosing, not yet on proving the drug works.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for GASTROESOPHAGEAL CANCER are added.
Genom att skicka in godkänner du våra Användarvillkor
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
Genom att skicka in godkänner du våra Användarvillkor
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
CHA University Bundang Medical Center
RECRUITINGSeongnam, Bundang, 13496, South Korea
-
Seoul National University Bundang Hospital
RECRUITINGSeongnam, Bundang, 13620, South Korea
-
Severance Hospital
RECRUITINGSeoul, Seoul, 03722, South Korea
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
DA-3501 (an experimental drug given by IV every three weeks)
What this could lead to
If it works, this could point toward a new treatment option for advanced stomach and pancreatic cancers that express a specific protein (CLDN18.2).
What could go wrong
This is a very early, first-in-human trial with only 51 participants. The drug may not shrink tumors or could cause serious side effects. Success is far from guaranteed.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.