New combo therapy targets Hard-to-Treat cancers
NCT ID NCT05383170
First seen Jan 08, 2026 · Last updated May 18, 2026 · Updated 20 times
Summary
This early-stage trial tested a new drug called CyPep-1, injected directly into tumors, combined with the immunotherapy pembrolizumab. It included 6 adults with advanced head and neck cancer, melanoma, or triple-negative breast cancer that had spread. The goal was to see if the combination is safe and shrinks tumors, both at the injection site and elsewhere in the body.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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AP-HM - Hôpital de la Timone
Marseille, France
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Azienda Ospedaliero Universitaria Senese
Siena, Italy
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CHRU de Besançon
Besançon, France
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CHU Lille
Lille, France
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Centre Leon Berard
Lyon, France
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City Of Hope
Duarte, California, 91010, United States
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Clinica Universidad de Navarra Madrid
Madrid, Spain
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Clinica Universidad de Navarra Pamplona
Pamplona, Spain
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EMC
Rotterdam, Netherlands
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Henry Ford Health System
Detroit, Michigan, 48202, United States
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Hospital Universitario 12 de Octubre
Madrid, Spain
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Hospital Universitario HM Sanchinarro
Madrid, Spain
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Hospital Universitario Virgen Macarena
Seville, Spain
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Houston Methodist
Houston, Texas, 77030, United States
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Hôpital Saint Louis - AP-HP
Paris, France
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Institut Bergonie
Bordeaux, France
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Institut Paoli Calmettes
Marseille, France
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Institute Gustave Roussy
Villejuif, France
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Istituto Europeo di Oncologia
Milan, Italy
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Maastricht UMC
Maastricht, Netherlands
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NKI/AvL
Amsterdam, Netherlands
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Texas Oncology - Baylor Charles A. Sammons Cancer Center
Dallas, Texas, 75246, United States
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University of Alabama at Birmingham
Birmingham, Alabama, 35294, United States
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University of Pittsburgh Medical Center
Pittsburgh, Pennsylvania, 15213-2582, United States
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Vall d'Hebron (VHIO)
Barcelona, Spain
Conditions
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