New cell therapy aims to tame deadly transplant complication

NCT ID NCT05643638

Recruiting now Disease control Sponsor: Cynata Therapeutics Limited Source: ClinicalTrials.gov ↗

First seen Jan 10, 2026 · Last updated May 22, 2026 · Updated 17 times

Summary

This study tests a new treatment called CYP-001 for people with a severe complication after a bone marrow or stem cell transplant, known as graft versus host disease (GvHD). The trial will compare CYP-001 plus standard steroids to steroids alone in 60 participants. The goal is to see if adding CYP-001 improves response rates and helps control the disease without needing more treatments.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

ASST Grande Ospedale Metropolitano Niguarda
RECRUITING

Milan, Italy
Anadolu Medical Center
RECRUITING

Eskişehir, Turkey (Türkiye)
Azienda Ospedaliero Universitaria delle Marche
RECRUITING

Ancona, Italy
BMT Group of Georgia
RECRUITING

Atlanta, Georgia, 30342, United States
Banner MD Anderson
COMPLETED

Phoenix, Arizona, 85012, United States
Cleveland Clinic
RECRUITING

Cleveland, Ohio, 44195, United States
Clínica Universidad de Navarra
RECRUITING

Pamplona, Spain
Dr Abdurrahman Yurtaslan Ankara Onkoloji Egitim ve Arastirma Hastanesi
RECRUITING

Yenimahalle, Turkey (Türkiye)
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
RECRUITING

Roma, Italy
Gayrettepe Florence Nightingale Hastanesi
COMPLETED

Istanbul, 34318, Turkey (Türkiye)
Hospital Claude Huriez
RECRUITING

Lille, France
Hospital Universitario Fundacion Jimenez Diaz
RECRUITING

Madrid, Spain
Hospital Universitario Ramon y Cajal
RECRUITING

Madrid, Spain
Hospital Universitario Virgen de la Arrixaca
RECRUITING

Murcia, Spain
Hospital Universitato De La Princesa
COMPLETED

Madrid, Spain
Hôpital Necker Enfants Malades
RECRUITING

Paris, France
Hôpital Universitaire Pitié-Salpêtrière
RECRUITING

Paris, France
ICO l'Hospitalet - Hospital Duran i Reynals
RECRUITING

Barcelona, Spain
IRCCS Ospedale Casa Sollievo della Sofferenza
RECRUITING

San Giovanni Rotondo, Italy
Istituto Clinico Humanitas
RECRUITING

Rozzano, Italy
Izmir Medicalpark Hospital
RECRUITING

Izmir, Turkey (Türkiye)
Karmanos Cancer Institute
RECRUITING

Detroit, Michigan, 48201, United States
Koc University
RECRUITING

Istanbul, Turkey (Türkiye)
Mayo Clinic Hospital
RECRUITING

Phoenix, Arizona, 85288, United States
Mayo Clinic Hospital
RECRUITING

Jacksonville, Florida, 32224, United States
Memorial Bahcelievler Hospital
COMPLETED

Istanbul, Turkey (Türkiye)
Memorial healthcare System
RECRUITING

Pembroke Pines, Florida, 33026, United States
Northwestern University
RECRUITING

Evanston, Illinois, 60208, United States
Ospedale dell'Angelo di Mestre
RECRUITING

Venezia, Italy
Penn State Health
RECRUITING

Hershey, Pennsylvania, 17033, United States
Royal Brisbane and Women's Hospital
ACTIVE_NOT_RECRUITING

Herston, Queensland, 4029, Australia
Royal Prince Alfred Hospital
COMPLETED

Sydney, New South Wales, 2050, Australia
University Of Nebrasaka Medical Center
RECRUITING

Omaha, Nebraska, 68198, United States
University of Arkansas Medical Center
RECRUITING

Little Rock, Arkansas, 72205, United States
University of Utah
RECRUITING

Salt Lake City, Utah, 84112, United States
Vilnius University Hospital Santaros Klinikos
RECRUITING

Vilnius, Lithuania
Weill Cornell Medicine - New York Presbyterian Hospital
COMPLETED

New York, New York, 10065, United States
Westmead Hospital
COMPLETED

Westmead, New South Wales, 2145, Australia
İnonu University
RECRUITING

Malatya, Turkey (Türkiye)

Conditions

Explore the condition pages connected to this study.

GRAFT VERSUS HOST DISEASE, ACUTE