Glue may seal veins and heal stubborn leg ulcers

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Primary insufficiency of the great saphenous vein (GVS) by a reflux\> 0.5 second from the inter-fascial saphenous trunk to the upper 1/3 of the thigh extending over the entire height of the thigh either in the saphenous compartment or in at least one extra-fascial tributary, in a standing patient, by compression of the calf * CEAP: C6, ulcer present on a single leg whose size can be captured by a simple photograph * Diameter of the GVS at the saphenofemoral junction ≥3 or ≤12 millimeters * Patient affiliated or beneficiary of a social security scheme * Patient having signed the informed consent Exclusion Criteria: * Patient with a circumferential ulcer * Patient with ipsilateral small saphenous vein insufficiency * Presenting a serious current pathology and / or a life expectancy of less than 5 years * History of deep or superficial vein thrombosis in the previous 6 months * Patient with arteriopathy obliterating of the affected lower limb, with an IPS \<0.8 or\> 1.3 * With post-thrombotic obstructive syndrome in the popliteal and / or femoral and / or iliac stage on the ipsilateral lower limb * Presenting primary or post-thrombotic axial deep venous reflux on the ipsilateral lower limb * Suspicion of non-post-thrombotic iliac compression on Doppler ultrasound * Contraindication to the intended treatment technique * Known allergy to cyanoacrylate glue or xylocaine * Patient with a BMI greater than 40 (morbid obesity) * Patient whose geographical distance is not compatible with the follow-up of the study * Pregnant or breastfeeding woman * Patient participating in another clinical study * Patient linguistically or psychically unable to understand the information given, to give informed consent or to answer the study questionnaires. * Protected patients: Adults under some guardianship or other legal protection; Hospitalized without consent