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Could bedside ECG and ultrasound replace chest X-Rays for central line checks?

NCT ID NCT07291869

Knowledge-focused Sponsor: York Teaching Hospitals NHS Foundation Trust Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether two bedside techniques—intracavity ECG and lung ultrasound—can safely confirm the position of a central venous catheter and rule out lung complications in intensive care patients. 75 adults needing a central line will be randomly assigned to standard care or the new methods. All will still get a chest X-ray for comparison. The goal is to see if these techniques are practical and reliable enough to use routinely.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could lead to faster, safer confirmation of central line placement without routine chest X-rays in critical care.
What could go wrong
This is a small feasibility study (75 people) testing whether the methods work in practice, not whether they improve outcomes. The techniques may not be reliable enough to replace standard care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 75 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2026

Expected to finish

Oct 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adult (aged ≥ 18 years) * Admitted, or planned for admission, to critical care * Requiring central venous catheter insertion as a part of their usual care * Suitable for both right or left internal jugular vein insertion Exclusion Criteria: * Previously randomised into CVC-TIP * Atrial fibrillation on 12-lead ECG * Cardiovascular instability, defined as * Noradrenaline dose \> 0.5mcg/kg/min * Rapidly escalating doses of vasopressors / inotropes * Difficulty in obtaining thoracic ultrasound images due to either * Weight \> 120kg * Existing pneumothorax (either side) * Subcutaneous emphysema * Wounds / dressing over anterior chest wall * Existing pacemaker * Non-English speaking participants * Death perceived as imminent * Any other reason as determined by treating clinician

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Central venous catheter Feasibility studies Intracavitary electrocardiogram guiding Point of care ultrasound (pocus)

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • York and Scarborough Teaching Hospitals NHS Foundation Trust

    RECRUITING

    York, North Yorkshire, YO31 8HE, United Kingdom

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