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Can turmeric ease pain after keyhole hysterectomy?

NCT ID NCT06886035

Symptom relief Sponsor: Erzincan Military Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed Phase 4 trial tested whether a turmeric extract (curcumin) can reduce pain after total laparoscopic hysterectomy. 126 participants took either liposomal curcumin or a placebo before and after surgery. The main goal was to measure pain levels 24 hours after the operation using a standard pain scale.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
liposomal curcumin (a turmeric extract)
What this could lead to
If it works, this could offer a low-cost, natural option to manage pain after laparoscopic hysterectomy, possibly reducing the need for stronger painkillers.
What could go wrong
This is a small, single-center trial with 126 participants. The effect may be modest or not better than placebo, and results may not apply to other surgeries or populations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Participants

126 people

The number who actually took part.

Started

Mar 2025

Finished

Jan 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 to 80 years

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: -Laparoscopic total hysterectomy and salpingectomy, with the option of additional procedures such as oophorectomy, uterosacral ligament plications, trans obturator tape insertion, or sentinel lymphadenectomy candidates * They should be able to understand and sign an informed consent * They should be literate enough to understand the maintenance of a diary recording pain scores, QoL-15 scores, and any adverse event Exclusion Criteria: * Patients with any peripheral or central neuropathic pain * Patients used to taking over-the-counter painkiller pills * Patients with a history of alcohol intake/drug dependence * Patients with a history of psychosis * Patients with chronic inflammatory diseases who cannot be taken off nonsteroidal anti-inflammatory drugs (NSAIDs)/painkillers • Patients on immunosuppressive/cytotoxic/steroid therapy. * American Society of Anesthesiologists physical status classification of ≥ IV * known hypersensitivity to curcumin; current opioid use for any indication; * concurrent procedures for deep infiltrating endometriosis, sacrocolpopexy, * concomitant intestinal surgery * refusal to participate.

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Conditions

The condition(s) this trial relates to.

agnosia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Pain management Postoperative care

Contacts and locations

Locations

  • Mugla Sıtkı Kocman University

    Muğla, 35460, Turkey (Türkiye)

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Other studies related to the condition(s) this trial covers.