Gene-Edited cells take on lupus and scleroderma in first human test
NCT ID NCT06925542
First seen Oct 31, 2025 · Last updated May 22, 2026 · Updated 23 times
Summary
This early-stage study tests a one-time treatment made from donor immune cells that are gene-edited to target and destroy faulty immune cells causing disease. It is for 80 adults with severe lupus, scleroderma, or myositis that have not responded to standard therapies. The main goal is to check safety and find the right dose, while also looking for signs that the treatment reduces disease activity.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Research Site 1
RECRUITINGSt Louis, Missouri, 63130, United States
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Research Site 2
RECRUITINGChicago, Illinois, 63110, United States
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Research Site 3
RECRUITINGHanover, 30625, Germany
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Research Site 4
RECRUITINGRedwood City, California, 94063, United States
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Research Site 5
RECRUITINGChapel Hill, North Carolina, 27599, United States
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Research Site 6
RECRUITINGBoston, Massachusetts, 02118, United States
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Research Site 7
NOT_YET_RECRUITINGAugsburg, 86156, Germany
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Research Site 8
RECRUITINGIowa City, Iowa, 52242, United States
Conditions
Explore the condition pages connected to this study.