New blood test could help monitor T-Cell lymphoma
NCT ID NCT06362148
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether a new blood test can find tiny bits of tumor DNA in people with T-cell lymphoma. The goal is to see if this test can help doctors track how well treatment is working and watch for signs of the cancer coming back. About 50 adults with newly diagnosed or returning lymphoma will give blood samples over two years.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 50 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Mar 2024
- Expected to finish
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Dec 2030
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients with peripheral T-cell lymphomas managed at tertiary care hospitals in Denmark.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients with newly diagnosed or relapsed/refractory peripheral T-cell lymphoma. * All primary systemic PTCL entities from the International Consensus Classification 2022. * ≥18 years of age. * Life expectancy of 3 months or longer. * ECOG performance status 0-4 at study entry (PS4 only if lymphoma-induced). * Measurable disease. * Written informed consent. Exclusion Criteria: * T-cell prolymphocytic leukemia * T-cell large granular lymphocytic leukemia * Chronic lymphoproliferative disorder of NK cells * Adult T-cell leukemia / lymphoma * Aggressive NK-cell leukemia * Primary cutaneous T-cell lymphoma such as Sézary syndrome and Mycosis fungoides. * Primary cutaneous CD30 positive T-cell lymphoproliferative disorders. * Lymphomatoid papulosis. * Primary cutaneous anaplastic large cell lymphoma. * Primary cutaneous small/medium CD4-positive T-cell lymphoproliferative disorder. * Primary cutaneous gamma-delta T-cell lymphoma. * Primary cutaneous acral CD8-positive T-cell lymphoproliferative disorder. * Primary cutaneous CD8-positive aggressive epidermotropic cytotoxic T-cell lymphoma. * History of active cancer during the past year, except basal cell carcinoma of the skin or stage 0 cervical carcinoma (in situ). * Unwillingness or inability to comply with the study protocol.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Department of Hematology, Aarhus University Hospital
Aarhus, Central Jutland, 8200, Denmark
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can a powerful combo of drugs and stem cell transplant beat tough lymphomas in kids?
- Can a simple blood test spot lymphoma earlier?
- Can a Five-Drug combo tame a tough lymphoma without standard chemo?
- Can a targeted pill boost Chemotherapy's punch against a rare lymphoma?