Could a CT scan replace invasive heart tests for some heart attack patients?
NCT ID NCT06689267
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether starting with a special CT scan (CT perfusion) could safely reduce the need for invasive heart catheterization in 180 patients with a mild type of heart attack called NSTEMI. Patients in the CT group first got a CT scan, and only those with concerning results went on to catheterization. The goal was to see if this approach could spare some patients from an unnecessary invasive procedure while still catching serious blockages.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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180 people
The number who actually took part.
- Started
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Dec 2024
- Finished
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Feb 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Patients with stable chest tightness or chest pain, aged ≥18 years 2. No ST elevation or dynamic ST-T changes on the ECG 3. Elevated TNT (greater than 14 ng/L three hours after symptom onset) Exclusion Criteria: 1. Persistent chest pain or ECG indicating dynamic ST-T changes, 2. Hemodynamic instability 3. Known history of coronary artery disease 4. Contraindications for CT perfusion or coronary angiography 5. Coexisting conditions such as pregnancy, cancer, severe valvular heart disease, or liver/kidney dysfunction 6. Other diseases with a life expectancy of less than one year 7. Inability to sign informed consent or, in the researcher's judgment, poor compliance, making it unlikely the patient can complete the study as required.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Zhongshan Hospital Fudan University
Shanghai, Shanghai Municipality, 200030, China
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Other studies related to the condition(s) this trial covers.
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