Study compares two colon screening methods for High-Risk patients
NCT ID NCT00748449
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study aimed to see if a CT scan of the colon (CT-colonography) is more acceptable than a standard colonoscopy for people at high risk of colorectal cancer. It included 39 patients with a personal or family history of advanced polyps or cancer. The main goal was to measure how many patients refused each procedure. The study was terminated early, so results are limited.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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39 people
The number who actually took part.
- Start date
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Jun 2008
- Finished
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Dec 2010
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Surveillance of patients with a personal history of advanced adenoma or CRC: * Informed consent obtained * Age ≥ 18 and ≤ 80 years old * History of advanced adenomatous polyps * Or history of non metastatic CRC with curative surgery and without other treatment more than 2 years before enrollment. * Previous medical examination Screening of patients with a Family history of CRC at high risk: * Informed consent obtained * Age ≥ 18 and ≤ 80 years old * First degree family history of colorectal cancer diagnosed \<60yrs during the five previous years-Previous medical examination Exclusion Criteria: Personal histories * Age \< 18 or \>80 years old * history of non adenomatous polyps * history of Metastatic CRC * familial adenomatous polyposis, Peutz-Jeghers syndrome, hereditary non polyposis colorectal cancer (HNPCC), juvenile polyposis syndrome * Familial history of familial adenomatous polyposis * Personal history of subtotal colectomy (but not of hemicolectomy, to confer to inclusion criteria) * Colonoscopy with a polyps resection dated more than 5 years and less than 2 years prior to enrollment. * Enrollment in another protocol * no health insurance affiliation Family histories * Age \< 18 or \>80 years old * Patients with one or several family histories of first degree colorectal cancer occured to unknown age or diagnosed after 60 years old. * Eligible patients having already undergone colonoscopy screening * no health insurance affiliation
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Cochin
Paris, 75014, France
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Other studies related to the condition(s) this trial covers.
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