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Freezing nerves may beat standard pain shots after lung surgery

NCT ID NCT07099469

Symptom relief Sponsor: University Hospital, Antwerp Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This small pilot study with 6 people compares two ways to manage pain after minimally invasive lung cancer surgery. One method uses a standard numbing injection (ropivacaine), while the other uses cryotherapy to freeze the nerves for longer-lasting pain relief (1-3 months). The goal is to see if cryotherapy reduces the need for pain medication and improves recovery.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 6 people

The number the study aims to enrol. It can still change while the study runs.

Started

Mar 2025

Expected to finish

Nov 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients referred for anatomical lung resection (lobectomy or segmentectomy) with the intention of performing it by robotic-assisted thoracoscopic surgery (RATS) are eligible for the trial.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Adult patients of 18 years or older who are able to give informed consent and fill out questionnaires in Dutch. Exclusion Criteria: * Patients who need an anatomic resection of the lung that's larger than one lung lobe, who have CPAM or infections. * Patients with chronic use (\>3 months) of strong opioids because of co-morbidities -for example, the use of tramadol is allowed. * If there's a high risk of conversion to a thoracotomy. This will be evaluated by the lung surgeon. * Patients who have had thoracic surgery in the past. * Patients with chronic kidney disease stage 4 or 5 (GFR \< 30 mL/min)

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Conditions

The condition(s) this trial relates to.

lung cancer Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Postoperative pain management Rats surgery

Contacts and locations

Locations

  • University Hospital Antwerp

    Edegem, Antwerp, 2560, Belgium

More trials for these conditions

Other studies related to the condition(s) this trial covers.