Freezing or cutting nerves: which works better for back pain?
NCT ID NCT07486674
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested two procedures—cryoablation (freezing nerves) and endoscopic denervation (cutting nerves)—to treat chronic sacroiliac joint pain. 51 adults with confirmed pain from the joint were included. The goal was to see which method better reduces pain and improves daily function.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- cryoablation and endoscopic denervation
- What this could lead to
- If successful, this could offer a more effective, longer-lasting option for people with chronic sacroiliac joint pain who haven't found relief from other treatments.
- What could go wrong
- This is a small, completed study with only 51 participants, so results may not apply to everyone. Both procedures are invasive and carry risks like infection or nerve damage.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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51 people
The number who actually took part.
- Started
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Apr 2023
- Finished
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Jan 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 85 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * adults aged 18 years or older * chronic sacroiliac joint pain * positive sacroiliac joint provocation maneuvers * positive diagnostic block of the dorsal branches of L5 and S1-S3 under fluoroscopic guidance * at least 70% pain relief after diagnostic block * ability to understand the study procedures and provide written informed consent Exclusion Criteria: * radicular pain caused by lumbar disc herniation or other dominant spinal pathology * spinal tumor, infection, fracture, or inflammatory spinal disease * coagulation disorder or ongoing anticoagulant therapy contraindicating the procedure * pregnancy * severe psychiatric or medical condition preventing reliable follow-up * refusal to participate in the study
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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EuroPainClinics Košice
Košice, Košice Region, 04011, Slovakia
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