Broccoli power: could cruciferous veggies stop bladder cancer return?
NCT ID NCT07391137
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether eating a diet rich in cruciferous vegetables (like broccoli, cauliflower, and cabbage) can help prevent bladder cancer from coming back in people with intermediate to very high-risk non-muscle invasive bladder cancer. About 250 participants will either follow this special diet or continue their usual eating habits, alongside standard treatment. The main goal is to see if the vegetable-rich diet improves the chance of staying cancer-free for at least one year.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
About 250 people
The number the study aims to enrol. It can still change while the study runs.
- Started
-
Oct 2025
- Expected to finish
-
May 2027
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 75 years
- Sex
-
Anyone
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Histologically confirmed Non-Muscle Invasive Bladder Cancer of Intermediate, High, or Very High risk according to the 2021 EAU NMIBC scoring model. * Age ≥ 18 Exclusion Criteria: * Low-Risk Non-Muscle Invasive Bladder Cancer * Muscle Invasive Bladder Cancer * Life expectancy \< 5 years * WHO performance status 3 or 4 * Variant histology * Concomitant Urothelial Bladder Cancer in the Upper-Urinary Tract * Prostate or bladder radiotherapy * Urinary tract infection * Chronic urinary retention or indwelling catheters * Other ongoing oncological diseases * Active oncological treatments in the past 12 months * Persistent disease (defined as residual disease detected within three months after TURB or at first cystoscopy) * Specific dietary restrictions such as a vegetarian diet, celiac disease, or lactose intolerance * Chronic Kidney Disease * Chronic inflammatory diseases such as Crohn's disease or ulcerative colitis * History of gastric resection * Hepatic disorders such as cirrhosis or ALT/AST levels three times above the upper normal limit * Thyroid disorders * Warfarin therapy
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Bladder cancer recurrence are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
S.Andrea Hospital of Rome
Rome, Lazio, 00135, Italy
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Lab-Grown tumor organoids could pick the right bladder chemo
- Can heated saline during bladder surgery stop tumors from coming back?
- Radiation instead of bladder removal: a new option for Hard-to-Treat bladder cancer?
- Can an immunotherapy plus chemotherapy keep High-Risk bladder cancer at bay?
- Can a bladder rinse before surgery keep bladder cancer at bay?
- Timing chemotherapy around bladder surgery may cut recurrence