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New hope for rare blood disorder: crovalimab trial shows promise in controlling PNH

NCT ID NCT04654468

First seen Nov 17, 2025 · Last updated Apr 30, 2026 · Updated 21 times

Summary

This study tests a new drug, crovalimab, in about 50 people with a rare blood disease called PNH. The goal is to see if the drug can control the destruction of red blood cells and reduce the need for blood transfusions. Participants receive crovalimab for at least 24 weeks, and the study measures how well the drug works and its safety.

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Contacts and locations

Locations

  • Institute of Hematology and Hospital of Blood Disease

    Tianjin, 300020, China

  • Tianjin Medical University General Hospital

    Tianjin, 300052, China

  • Union Hospital Tongji Medical College Huazhong University of Science and Technology

    Wuhan, 430022, China

  • West China Hospital, Sichuan University

    Chengdu, 610041, China

Conditions

Explore the condition pages connected to this study.