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Hope for RVCL: experimental drug targets deadly genetic condition

NCT ID NCT04611880

First seen May 08, 2026 · Last updated May 24, 2026 · Updated 4 times

Summary

This study tested a drug called crizanlizumab in 18 adults with RVCL, a rare and fatal genetic disease that damages small blood vessels in the brain and eyes. The goal was to see if the drug could slow the growth of brain lesions seen on MRI scans. There is currently no treatment for RVCL, and this trial aimed to find a way to control the disease.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Andria Ford

    St Louis, Missouri, 63110, United States

  • Perelman School of Medicine; University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

Conditions

Explore the condition pages connected to this study.