Could a common supplement ease fibromyalgia pain?
NCT ID NCT06675708
First seen Jul 29, 2026 · Last updated Jul 30, 2026 · Updated 1 time
Summary
This trial tests whether daily creatine supplements can reduce pain, fatigue, and muscle weakness in people with fibromyalgia. Eighty adults diagnosed with fibromyalgia will receive either creatine or a placebo for a set period. Researchers will measure changes in pain levels, muscle strength, sleep quality, and overall well-being to see if creatine offers any benefit.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- creatine dietary supplement
- What this could lead to
- If it works, creatine could become a simple, low-cost option to help manage fibromyalgia symptoms like pain, fatigue, and muscle weakness.
- What could go wrong
- This is a small, early-stage trial. Creatine may not outperform placebo, and results may not apply to all fibromyalgia patients. Side effects are possible.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
80 people
The number who actually took part.
- Started
-
Feb 2025
- Finished
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Jun 2026
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 75 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Diagnosed with FM * aged between 18 and 75 years * agree to participate and sign the informed consent Exclusion Criteria: * who do not have recent surgeries * patients with reduced mobility * adequate level of comprehension to be able to answer the questionnaires that will be provided in the study * If they are taking antihypertensive medications
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University Camilo José Cela
Madrid, 28692, Spain
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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