Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

Which breathing support works best for sick babies?

NCT ID NCT04677556

Knowledge-focused Sponsor: Assistance Publique - Hôpitaux de Paris Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at 20 infants with severe bronchiolitis (a serious lung infection) to compare two types of breathing support: CPAP and NiPPV. The goal was to see which method reduces the effort of breathing more effectively. Researchers measured breathing effort using a special tube in the esophagus. The findings could help doctors choose the best treatment to avoid putting babies on a breathing tube.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

20 people

The number who actually took part.

Started

Jan 2021

Finished

Jan 2022

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

Up to 6 months

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Clinical and radiological diagnosis of bronchiolitis * Need for non-invasive ventilation support (NiPPV or CPAP) with a modified Wood clinical asthma score (m-WCAS)\> 4 and / or hypercapnic acidosis (pH \<7.3 and / or pCO2\> 50mmHg) * Written parental informed consent Exclusion Criteria: * Contraindication to nasogastric tube (recent surgery of the esophagus, esophageal malformation at risk of perforation, severe coagulopathy) * Absolute or relative contraindication to NIV * Respiratory collapse: coma (GCS \<12) and / or more than 3 apneas per hour with bradycardia \<90 / min and / or SpO2 \<90% * Pneumothorax * Preexisting disorder that may influence WOB * Neuromuscular disease * Chronic respiratory failure already under NIV or tracheostomy at home * No social security

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Severe viral bronchiolitis are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

acute bronchiolitis bronchiolitis Bronchiolitis, Viral

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Severe viral bronchiolitis

Contacts and locations

Locations

  • Hôpital Necker-Enfants Malades

    Paris, 75015, France