Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

Can a sleep machine stop heart rhythm problems after ablation?

NCT ID NCT07444372

Disease control Sponsor: Beijing Anzhen Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether using a CPAP machine for sleep apnea after a heart procedure (catheter ablation) can help prevent atrial fibrillation from coming back. About 658 adults with both conditions will be randomly assigned to use CPAP for a year or receive usual care. The goal is to see if CPAP reduces the chance of irregular heart rhythms.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Continuous Positive Airway Pressure (CPAP) device
What this could lead to
If it works, this could provide a clear way to lower the chance of atrial fibrillation returning after ablation in people with sleep apnea.
What could go wrong
Previous small trials have not shown a clear benefit, possibly because patients didn't use the CPAP enough. This trial is still recruiting, and results may not apply to everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 658 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2026

Expected to finish

Jan 2029

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 75 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Patients must meet all of the following conditions to be eligible for the study: * Age 18-75 years. * Patients with persistent AF scheduled for first-time catheter ablation. * Diagnosed with OSA. * Able to tolerate CPAP therapy. * Capable of understanding and complying with the study protocol. * Willing to sign the informed consent form. Exclusion Criteria: Patients meeting any of the following criteria will be excluded from the study: * Secondary AF. * Left atrial anteroposterior diameter 60mm (measured via parasternal long-axis view). * Left ventricular ejection fraction \< 30%. * Comorbid moderate-to-severe mitral stenosis or history of prosthetic valve replacement (mechanical or bioprosthetic). * Pregnant or breastfeeding women. * History of myocardial infarction, percutaneous coronary intervention, or cardiac surgery within 3 months prior to screening. * History of stroke or transient ischemic attack within 6 months prior to screening. * Perioperative complications related to the ablation procedure occurring prior to randomization. * Inability to discontinue antiarrhythmic drugs (AADs) post-procedure due to other reasons. * Life expectancy \< 1 year. * Central sleep apnea. * Conditions requiring ventilatory support, including obesity hypoventilation syndrome (defined as BMI \> 30kg/m² and awake PaCO₂ \> 45mmHg), amyotrophic lateral sclerosis, or chronic obstructive pulmonary disease with \> 1 episode of respiratory failure or hypercapnia. * Treatment-emergent central sleep apnea during CPAP tolerance assessment that cannot be corrected prior to randomization. * Receipt of instrumental or surgical treatment for OSA within 3 months prior to screening, including CPAP, oral appliances, ENT surgery, or bariatric surgery. * Use of glucagon-like peptide-1 receptor agonists, glucose-dependent insulinotropic peptide receptor agonists, or glucagon receptor agonists for weight loss within 3 months prior to screening, or plans to initiate such medications within the next year. * Current participation in other drug or device trials.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Arrhythmia are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

Arrhythmias, Cardiac atrial fibrillation cardiac rhythm disease obstructive sleep apnea syndrome sleep apnea syndrome sleep disorder sleep-wake disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Arrhythmia Atrial fibrillation (AF) Continuous positive airway pressure Obstructive sleep apnea Sleep disorder (disorder) Sleep-disordered breathing (SDB)

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    27 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Beijing Anzhen Hospital

    RECRUITING

    Beijing, Beijing Municipality, 100029, China

  • Beijing Chaoyang Hospital, Capital Medical University

    NOT_YET_RECRUITING

    Beijing, Beijing Municipality, 100020, China

  • Beijing Hospital

    NOT_YET_RECRUITING

    Beijing, Beijing Municipality, 100730, China

  • Beijing Jishuitan Hospital

    NOT_YET_RECRUITING

    Beijing, Beijing Municipality, 100035, China

  • First Affiliated Hospital of China Medical University

    NOT_YET_RECRUITING

    Shenyang, Liaoning, 110001, China

  • First Affiliated Hospital of Dalian Medical University

    NOT_YET_RECRUITING

    Dalian, Liaoning, 116011, China

  • First Affiliated Hospital of Fujian Medical University

    NOT_YET_RECRUITING

    Fuzhou, Fujian, 350004, China

  • First Affiliated Hospital of Ningbo University

    NOT_YET_RECRUITING

    Ningbo, Zhejiang, 315010, China

  • Fujian Medical University Union Hospital

    NOT_YET_RECRUITING

    Fuzhou, Fujian, 350001, China

  • Langfang People's Hospital

    NOT_YET_RECRUITING

    Langfang, Hebei, 065000, China

  • Linyi People's Hospital

    NOT_YET_RECRUITING

    Linyi, Shandong, 276003, China

  • Peking University International Hospital

    NOT_YET_RECRUITING

    Beijing, Beijing Municipality, 102206, China

  • People's Hospital of Guangxi Zhuang Autonomous Region

    NOT_YET_RECRUITING

    Nanning, Guangxi, 530021, China

  • Second Affiliated Hospital of Harbin Medical University

    NOT_YET_RECRUITING

    Harbin, Heilongjiang, 150086, China

  • Second Hospital of Shanxi Medical University

    NOT_YET_RECRUITING

    Taiyuan, Shanxi, 030001, China

  • Shengjing Hospital of China Medical University

    NOT_YET_RECRUITING

    Shenyang, Liaoning, 110004, China

  • Shengli Oilfield Central Hospital

    NOT_YET_RECRUITING

    Dongying, Shandong, 257034, China

  • Shijiazhuang Great Wall Hospital of Integrated Traditional Chinese and Western Medicine

    NOT_YET_RECRUITING

    Shijiazhuang, Hebei, 050000, China

  • The First Affiliated Hospital of Nanjing Medical University

    NOT_YET_RECRUITING

    Nanjing, Jiangsu, 210029, China

  • The First Affiliated Hospital of Zhengzhou University

    NOT_YET_RECRUITING

    Zhengzhou, Henan, 450052, China

  • The First Hospital of Jilin University

    NOT_YET_RECRUITING

    Changchun, Jilin, 130021, China

  • The Ninth Hospital of Xingtai

    NOT_YET_RECRUITING

    Xingtai, Hebei, 055250, China

  • The Second Xiangya Hospital of Central South University

    NOT_YET_RECRUITING

    Changsha, Hunan, 410011, China

  • Tianjin Chest Hospital

    NOT_YET_RECRUITING

    Tianjin, Tianjin Municipality, 300222, China

  • Wuhan Asia General Hospital

    NOT_YET_RECRUITING

    Wuhan, Hubei, 430056, China

  • Wuhan No. 1 Hospital

    NOT_YET_RECRUITING

    Wuhan, Hubei, 430014, China

  • Zhangzhou Hospital of Fujian Province

    NOT_YET_RECRUITING

    Zhangzhou, Fujian, 363000, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.