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New Self-Amplifying RNA vaccine shows promise in massive COVID-19 trial

NCT ID NCT05012943

First seen Nov 06, 2025 · Last updated May 01, 2026 · Updated 24 times

Summary

This large study tested a new COVID-19 vaccine called ARCT-154 in nearly 20,000 adults in Vietnam. The vaccine uses self-amplifying RNA technology to teach the body to fight the virus. Researchers checked for side effects, immune response, and how well it prevented COVID-19 compared to a placebo and another approved vaccine.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Hanoi Medical University

    Hanoi, Hanoi, 00000, Vietnam

  • Military Medical University

    Hanoi, Hanoi, 00000, Vietnam

  • Pasteur Institute

    Ho Chi Minh City, Ho Chi Minh, 00000, Vietnam

Conditions

Explore the condition pages connected to this study.