Long COVID mystery: study follows mild cases for a year
NCT ID NCT04813731
First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This completed study followed 300 adults who had mild to moderate COVID-19 but were not hospitalized. Researchers tracked their symptoms for up to a year to see how long it took to fully recover and how lingering symptoms affected daily life. The goal was to better understand long COVID in primary care patients.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this study could help doctors better predict and manage long COVID in patients who had mild or moderate infections.
- What could go wrong
- This is an observational study, not a treatment trial. It cannot prove what causes lingering symptoms or how to fix them.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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300 people
The number who actually took part.
- Started
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Dec 2020
- Finished
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Jun 2022
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Adult patients over all age categories with laboratory confirmed SARS-CoV-2 infection and symptoms consistent with COVID-19
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Confirmed SARS-CoV-2 infection, either by polymeras chain reaction (PCR), or by antigen testing (if authorized/recommended/used by national/local governments) * Symptoms consistent with mild to moderate COVID-19 * Maximum of 2 weeks since positive SARS-CoV-2 test * Aged 18 years and older * Patient able and willing to comply with monthly phone calls. Exclusion Criteria: * Hospitalisation due to COVID-19
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Balan Medfam SRL
Cluj-Napoca, Romania
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Center for General Practice at Aalborg University
Aalborg, Denmark
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Centre for General Practice, Department of Family Medicine & Population Health (FAMPOP), Faculty of Medicine and Health Sciences, University of Antwerp
Antwerp, Belgium
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Covid-19 primary care special unit Sassuolo, Azienda Unità Sanitaria locale di Modena, Modena, Italy
Modena, Italy
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Département de Santé Publique, Université Côte d'Azur, Centre Hospitalier Universitaire de Nice, Nice, France
Nice, France
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Institut für Allgemeinmedizin Universitätsklinikum Würzburg Josef-Schneider-Str. 2/D7 97080 Würzburg
Würzburg, Germany
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Julius Center, University Medical Center Utrecht
Utrecht, Netherlands
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Kärna Primary Health Care Centre
Linköping, Sweden
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Medical University of Lodz, Lodz
Lodz, Poland
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R. Lugar Center for Public Health Research
Tbilisi, Georgia
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School of Medicine, National University of Ireland
Galway, Ireland
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Wetterhälsan Primary Health Care Centre
Jönköping, Sweden
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the Academic Centre for General Practice (ACHG), Department of Public Health and Primary Care, KU Leuven
Leuven, Belgium
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