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Volunteers exposed to omicron in controlled study to find optimal dose

NCT ID NCT06478420

First seen Nov 18, 2025 · Last updated May 22, 2026 · Updated 29 times

Summary

This study gives healthy volunteers who have had a COVID-19 vaccine or prior infection a small dose of the Omicron BA.5 virus through the nose. The goal is to find the right dose that causes infection in 50-75% of people and to monitor safety and how the virus spreads. 45 participants aged 18-40 will be closely watched in quarantine to learn more about the virus in immune-experienced individuals.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Centre for Clinical Vaccinology and Tropical Medicine

    Oxford, Oxfordshire, OX3 7LE, United Kingdom

Conditions

Explore the condition pages connected to this study.