Scientists to deliberately infect volunteers with omicron to speed up vaccine testing
NCT ID NCT07397455
First seen Feb 14, 2026
Summary
This study will give healthy, vaccinated adults aged 18-50 a small dose of the Omicron EG.5.1 virus through nose drops to see how many develop a mild infection. The goal is to create a safe, controlled model for testing future COVID-19 vaccines and treatments. Participants will stay in quarantine for 10-12 days and be monitored for 6 months.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
SARS-CoV-2 Omicron EG.5.1 virus (given as nose drops)
What this could lead to
If successful, this study could create a safe human infection model to rapidly test new COVID-19 vaccines and treatments without waiting for natural outbreaks.
What could go wrong
This is a very early Phase 1 study with only 38 participants. The virus may not cause infection at the desired rate, and results may not apply to other variants or populations.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.