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New couples therapy aims to curb veteran suicide

NCT ID NCT04816149

Disease control Sponsor: VA Office of Research and Development Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a new therapy called TR&ST that involves both a veteran at risk for suicide and their romantic partner. The goal was to see if working together as a couple could reduce suicidal thoughts more than standard VA care. The study included 104 veterans and their partners and measured changes in suicidal thinking and communication over several months.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Couples-based therapy (Treatment for Relationships and Safety Together, TR&ST)
What this could lead to
If successful, this could provide a new, effective way to reduce suicidal thoughts in veterans by involving their intimate partners in therapy.
What could go wrong
This was a small, early-stage pilot study with only 104 participants. The results may not apply to all veterans or couples, and the therapy may not be more effective than standard care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

104 people

The number who actually took part.

Started

Apr 2021

Finished

Mar 2026

Lead sponsor

A government agency

The lead sponsor is a US federal agency other than the NIH.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Veterans who report present suicidal ideation CSSR-S \> 2 ("Active thoughts of killing oneself") in past 1 month at phone screen and/or a suicide attempt in the prior 3 months, and * an intimate partner who is willing to participate. * Additional inclusion criteria for both Veterans and Partners include: * in the committed relationship for at least 6 months * plans to remain in the San Diego region for 7 months * capable of informed consent * agree to have assessment and treatment sessions audio recorded. Exclusion Criteria: The following are our Exclusion Criteria for both Veterans and Partners: * not English speaking * cannot complete the assessment battery * current substance use requiring immediate detoxification or outpatient plan directed specifically to residential substance use disorder (not mental health) services * has or meets criteria for a current diagnosis of psychosis and/or mania in either member of the couple * under conservatorship requiring proxy consent * any perpetration of severe physical or sexual relationship aggression in the past year (as assessed by the CTS-2)

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Conditions

The condition(s) this trial relates to.

Suicide

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Interpersonal relations Suicide

Contacts and locations

Locations

  • VA San Diego Healthcare System, San Diego, CA

    San Diego, California, 92161-0002, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.