New throat sprays aim to soothe your cold cough
NCT ID NCT07330856
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests two throat sprays (CDN and CW) for adults with a cough from a viral cold. About 58 people will use one of the sprays for 7 days and report how well it works and any side effects. The goal is to see if these sprays are safe and help ease cough symptoms.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 4
Runs after approval, following long-term safety and how well the treatment works in everyday use.
- Participants
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About 58 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jan 2026
- Expected to finish
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Mar 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Male or female, * Aged 18 to 65 years, * Presenting with an acute dry or productive cough for less than 3 weeks, associated with one of the following viral conditions: Acute viral rhinitis, Acute viral rhinopharyngitis, Acute viral tonsillitis, Acute viral pharyngitis / tonsillitis, * For patients with suspected pharyngitis/tonsillitis: McIsaac score \< 2 or a negative rapid antigen detection test for Group A beta-hemolytic Streptococcus, * Effective contraception for female patients of childbearing potential, * Sufficient cooperation and understanding to comply with the requirements of the trial, * Acceptance of registration in the SI-RIPH database (Système d'Information pour la Recherche sur les Produits de Santé), * Having received clear information and agreeing to provide written informed consent, * Covered by the French national health insurance system Exclusion Criteria: * Hypersensitivity or history of allergy to any component of the investigational products, * Severe, poorly tolerated cough, * Complicated acute rhinitis (e.g., acute bacterial sinusitis, acute otitis media, acute bronchitis, or pneumonia), * Chronic or allergic rhinosinusitis, * Bacterial tonsillitis or pharyngitis, * Positive antigen test for influenza A/B or COVID-19 requiring etiological treatment per current guidelines (Appendix 5), * Concurrent use of antitussives, bronchodilators, inhaled corticosteroids, other pulmonary-targeted therapies, or medications known to induce cough (such as ACE inhibitors, ARBs, etc.), antibiotics, antivirals, or any other treatment deemed incompatible with the study by the investigator, * Recent ENT surgery (\<6 months), * Pulmonary disease (e.g., COPD, asthma), * Immunodeficiency (based on patient declaration), * Comorbidities or a health status judged incompatible with the trial by the investigator (e.g., Gastroesophageal Reflux Disease \[GERD\] or abnormal lung auscultation), * Pregnant or breastfeeding women, * Regular tobacco smoker (as judged by the investigator), * Current participation in another clinical trial, being in an exclusion period from a previous trial, or having received total compensation exceeding 6000 euros in the 12 months prior to study start, * Under legal protection measures (guardianship, trusteeship, deprivation of liberty, judicial safeguard).
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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CHU de Clermont-ferrand
RECRUITINGClermont-Ferrand, 63000, France
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Other studies related to the condition(s) this trial covers.
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- Can a simple breathing test unlock the secrets of chronic cough?
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