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UK migraine study tracks Real-World rimegepant relief

NCT ID NCT06898047

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study follows 250 adults in the UK who already use rimegepant for migraine attacks. Over 12 weeks, they report how quickly the drug eases pain and other symptoms. The goal is to see how consistently rimegepant works in everyday life.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Rimegepant (oral lyophilisate)
What this could lead to
If successful, this study could confirm how reliably rimegepant works for acute migraine in real-world UK settings, supporting its use.
What could go wrong
This is an observational study, not a controlled trial, so results may be less definitive. It only follows people already using the drug, so no new treatment is being tested.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 250 people

The number the study aims to enrol. It can still change while the study runs.

Started

Nov 2025

Expected to finish

Jul 2026

An estimate. End dates often move.

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adult participants living in the United Kingdom, with a migraine diagnosis confirmed by a healthcare professional, experiencing at least 4 migraine attacks per month, with a current prescription of rimegepant for acute treatment of migraine, and, if receving preventive migraine treatment, must be stable before enrollment. Participants will be excluded if they are currently using rimegepant as preventive migraine treatment, if present other specific neurological conditions, if currently prescribed with drugs that may indude or inhibits CYP3A4, or if they are participating in a migraine-related clinical trial. All participants enrolled must acknowledge their participation in the study informed consent.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion criteria 1. UK resident. 2. At least 18 years of age. 3. Migraine diagnosis confirmed by healthcare professional. 4. Current prescription of rimegepant for acute treatment of migraine. 5. Experienced at least 4 migraine attacks per month prior to study enrolment. 6. In the case of participants receiving preventive migraine treatment: * For oral preventives, the treatment must be "stable" i.e., final dosing regimen has been found. * For migraine preventives administered monthly, the participant must have had their most recent treatment within the 3 weeks prior to study enrolment. * For migraine preventives administered quarterly, the participant must have had their most recent treatment within the 2 months prior to study enrolment. * If the last treatment is not within the stipulated period, participants will be asked to provide the date of the next scheduled treatment, after which the participant may be invited back to enrol into the study. 7. Evidence of a personally signed (or acknowledged if obtained electronically or online) and dated informed consent document indicating that the participant has been informed of all pertinent aspects of the study. Exclusion criteria 1. Current use of rimegepant as a preventive migraine medication. 2. Current diagnosis of any of the following conditions: * new daily persistent headache * chronic daily headache * cluster headache * post-traumatic headache * hemicrania continua * major depression * pain syndromes other than migraine (e.g. fibromyalgia) * psychiatric conditions (e.g., schizophrenia) * dementia * significant neurological disorders other than migraine. 3. Current prescription of any of the following medications: * Strong inhibitors of CYP3A4 * Strong or moderate inducers of CYP3A4 4. Patients participating in a migraine-related clinical trial.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Pfizer

    London, United Kingdom

More trials for these conditions

Other studies related to the condition(s) this trial covers.