Night owl fix: melatonin may lift mood in bipolar disorder
NCT ID NCT06226025
First seen Nov 01, 2025 · Last updated May 22, 2026 · Updated 24 times
Summary
This study tests whether a low-dose melatonin supplement, combined with a behavioral sleep program, can shift the body clock earlier and improve mood and sleep in people with bipolar disorder. About 50 adults with bipolar I or II who are evening types and have mild depression will take either melatonin or a placebo for 4 weeks. The goal is to see if this approach can ease depressive symptoms and reset sleep timing.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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University of Michigan
RECRUITINGAnn Arbor, Michigan, 48109, United States
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